Structure of PDB 4lvj Chain A Binding Site BS03

Receptor Information
>4lvj Chain A (length=192) Species: 1311 (Streptococcus agalactiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYMVARMQKMKAGNLGGAFKHNERVFSNKDINPSRSHLNYELTDRDRSVS
YEKQIKDYVNENKVSNRAIRKDAVLCDEWIITSDKDFFEKLDEEQTRTFF
ETAKNYFAENYGESNIAYASVHLDESTPHMHMGVVPFENGKLSSKAMFDR
EELKHIQEDLPRYMSDHGFELERGKLNSEAKHKTVAEFKRAM
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4lvj Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4lvj Structural basis of a histidine-DNA nicking/joining mechanism for gene transfer and promiscuous spread of antibiotic resistance.
Resolution2.17 Å
Binding residue
(original residue number in PDB)		H22 H126 E129 H133 H135
Binding residue
(residue number reindexed from 1)		H21 H122 E125 H129 H131
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4lvj, PDBe:4lvj, PDBj:4lvj
PDBsum4lvj
PubMed28739894
UniProtP13925|PRE_STRAG Plasmid recombination enzyme (Gene Name=pre)

[Back to BioLiP]