Structure of PDB 4lmg Chain A Binding Site BS03

Receptor Information
>4lmg Chain A (length=120) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVAC
PFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKN
DEKAIKTFDELEYKASLNLP
Ligand information
Receptor-Ligand Complex Structure
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PDB4lmg Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
R76 D78 K81 R112
Binding residue
(residue number reindexed from 1)
R35 D37 K40 R53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process
GO:0010106 cellular response to iron ion starvation
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:4lmg, PDBe:4lmg, PDBj:4lmg
PDBsum4lmg
PubMed24591629
UniProtQ08957|AFT2_YEAST Iron-regulated transcriptional activator AFT2 (Gene Name=AFT2)

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