Structure of PDB 4l58 Chain A Binding Site BS03

Receptor Information
>4l58 Chain A (length=65) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPR
NLDKERAVLLQRRKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4l58 Chain A Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4l58 Molecular basis for chromatin binding and regulation of MLL5.
Resolution1.48 Å
Binding residue
(original residue number in PDB)		C5 C7 H27 C30
Binding residue
(residue number reindexed from 1)		C5 C7 H27 C30
Annotation score4
Enzymatic activity
Enzyme Commision number 2.1.1.43: Transferred entry: 2.1.1.354.
External links
PDB RCSB:4l58, PDBe:4l58, PDBj:4l58
PDBsum4l58
PubMed23798402
UniProtQ8IZD2|KMT2E_HUMAN Inactive histone-lysine N-methyltransferase 2E (Gene Name=KMT2E)

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