Structure of PDB 4kil Chain A Binding Site BS03

Receptor Information
>4kil Chain A (length=200) Species: 985958 (Influenza A virus (A/Lima/WRAIR1695P/2009(H1N1))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVC
FMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSIC
NTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHI
HIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE
Ligand information
Ligand ID1R5
InChIInChI=1S/C15H10FNO2/c16-12-5-3-9(4-6-12)10-1-2-11-8-14(18)15(19)17-13(11)7-10/h1-8,18H,(H,17,19)
InChIKeyYFFXAOFQLPIPER-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC1=Cc2ccc(cc2NC1=O)c3ccc(F)cc3
OpenEye OEToolkits 1.7.6c1cc(ccc1c2ccc3c(c2)NC(=O)C(=C3)O)F
ACDLabs 12.01Fc3ccc(c1ccc2c(c1)NC(=O)C(O)=C2)cc3
FormulaC15 H10 F N O2
Name7-(4-fluorophenyl)-3-hydroxyquinolin-2(1H)-one
ChEMBLCHEMBL2386739
DrugBank
ZINCZINC000095920752
PDB chain4kil Chain A Residue 305 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4kil 3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		I38 H41 E80 D108 E119 K134
Binding residue
(residue number reindexed from 1)		I43 H46 E85 D113 E124 K139
Annotation score1
Binding affinityMOAD: ic50=0.5uM
PDBbind-CN: -logKd/Ki=6.30,IC50=0.5uM
Gene Ontology
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UnboundLocalError		Python 3.6.8: /usr/bin/python3
Fri Nov 15 12:41:14 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '4kil', asym_id = 'A', bs = 'BS03', title = '3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease.'
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='4kil', asym_id='A', bs='BS03', title='3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease.')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0003723,0039694', uniprot = '', pdbid = '4kil', asym_id = 'A'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003723,0039694', uniprot='', pdbid='4kil', asym_id='A')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>