Structure of PDB 4gv9 Chain A Binding Site BS03

Receptor Information
>4gv9 Chain A (length=198) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIH
FFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQ
GSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGV
VVEKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRPRVVL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4gv9 Chain E Residue 103 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4gv9 Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
Resolution2.46 Å
Binding residue
(original residue number in PDB)		D389 E391 D533
Binding residue
(residue number reindexed from 1)		D27 E29 D165
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.13.-
External links
PDB RCSB:4gv9, PDBe:4gv9, PDBj:4gv9
PDBsum4gv9
PubMed23615902
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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