Structure of PDB 4gv6 Chain A Binding Site BS03

Receptor Information
>4gv6 Chain A (length=207) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMDHVEFGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQP
SSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPR
NMVITCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDL
CHMHTGVVVEKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFR
TSPRVVL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4gv6 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4gv6 Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
Resolution1.98 Å
Binding residue
(original residue number in PDB)		E399 C506 H509 C529
Binding residue
(residue number reindexed from 1)		E44 C151 H154 C168
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.13.-
External links
PDB RCSB:4gv6, PDBe:4gv6, PDBj:4gv6
PDBsum4gv6
PubMed23615902
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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