Structure of PDB 4g1p Chain A Binding Site BS03

Receptor Information
>4g1p Chain A (length=479) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSHSLTSVFQKIDSLKPQFFSRLTKAIQIPAVSSDESLRSKVFDKAKFIS
EQLSQSGFHDIKMVDLGIQPPPSTPNLSLPPVILSRFGSDPSKKTVLVYG
HYDVQPAQLEDGWDTEPFKLVIDEAKGIMKGRGVTDDTGPLLSWINVVDA
FKASGQEFPVNLVTCFEGMEESGSLKLDELIKKEANGYFKGVDAVCISDN
YWLGTKKPVLTYGLRGCNYYQTIIEGPSADLHSGIFGGVVAEPMIDLMQV
LGSLVDSKGKILIDGIDEMVAPLTEKEKALYKDIEFSVEELNAATGSKTS
LYDKKEDILMHRWRYPSLSIHGVEGAFSAQGAKTVIPAKVFGKFSIRTVP
DMDSEKLTSLVQKHCDAKFKSLNSPNKCRTELIHDGAYWVSDPFNAQFTA
AKKATKLVYGVDPDFTREGGSIPITLTFQDALNTSVLLLPMGRGDDGAHS
INEKLDISNFVGGMKTMAAYLQYYSESPE
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain4g1p Chain A Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4g1p Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae
Resolution2.547 Å
Binding residue
(original residue number in PDB)		E171 H450
Binding residue
(residue number reindexed from 1)		E170 H449
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.13.-
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008242 omega peptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016805 dipeptidase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070573 metallodipeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006751 glutathione catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4g1p, PDBe:4g1p, PDBj:4g1p
PDBsum4g1p
PubMed
UniProtP43616|DUG1_YEAST Cys-Gly metallodipeptidase DUG1 (Gene Name=DUG1)

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