Structure of PDB 4ff3 Chain A Binding Site BS03

Receptor Information
>4ff3 Chain A (length=1095) Species: 10752 (Enquatrovirus N4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EELKEGIDAVYPSLVGTADSKAEGIKNYFKLSFTLPEEQKSRTVGSEAPL
KDVAQALSSRARYELFTEKETANPAFNGEVIKRYKELMEHGEGIADILRS
RLAKFLNTKDVGKRFAQGTEANRWVGGKLLNIVEQDGDTFKYNEQLLQTA
VLAGLQWRLTATSNTAIKDAKDVAAITGIDQALLPEGLVEQFDTGMTLTE
AVSSLAQKIESYWGLSRNPNAPLGYTKGIPTAMAAEILAAFVESTDVVEN
IVDMSEIDPDNKKTIGLYTITELDSFDPINSFPTAIEEAVLVNPTEKMFF
GDDIPPVANTQLRNPAVRNTPEQKAALKAEQATEFYVHTPMVQFYETLGK
DRILELMGAGTLNKELLNDNHAKSLEGKNRSVEDSYNQLFSVIEQVRAQS
EDISTVPIHYAYNMTRVGRMQMLGKYNPQSAKLVREAILPTKATLDLSNQ
NNEDFSAFQLGLAQALDIKVHTMTREVMSDELTKLLEGNLKPAIDMMVEF
NTTGSLPENAVDVLNTALGDRKSFVALMALMEYSRYLVAEDKSAFVTPLY
VEADGVTNGPINAMMLMTGGLFTPDWIRNIAKGGLFIGSPNKTMNEHRST
ADNNDLYQASTNALMESLGKLRSNYASNMPIQSQIDSLLSLMDLFLPDIN
LGENGALELKRGIAKNPLTITIYGSGARGIAGKLVSSVTDAIYERMSDVL
KARAKDPNISAAMAMFGKQAASEAHAEELLARFLKDMETLTSTVPVKRKG
VLELQSTGTGAKGKINPKTYTIKGEQLKALQENMLHFFVEPLRNGITQTV
GESLVYSTEQLQKATQIQSVVLEDMFKQRVQEKLAEKAKDPTWKKGDFLT
QKELNDIQASLNNLAPMIETGSQTFYIAGSENAEVANQVLATNLDDRMRV
PMSIYAPAQAGVAGIPFMTIGTGDGMMMQTLSTMKGAPKNTLKIFDGMNI
GLNDITDASRKANEAVYTSWQGNPIKNVYESYAKFMKNVDFSKLSPEALE
AIGKSALEYDQRENATVDDIANAASLIERNLRNIALGVDIRHKVLDKVNL
SIDQMAAVGAPYQNNGKIDLSNMTPEQQADELNKLFREELEARKQ
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4ff3 Chain A Residue 1202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ff3 Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography.
Resolution1.997 Å
Binding residue
(original residue number in PDB)		D559 D951
Binding residue
(residue number reindexed from 1)		D554 D946
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
External links
PDB RCSB:4ff3, PDBe:4ff3, PDBj:4ff3
PDBsum4ff3
PubMed23235152
UniProtQ859P9|RPOLV_BPN4 Virion DNA-directed RNA polymerase (Gene Name=50)

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