Structure of PDB 4e7l Chain A Binding Site BS03

Receptor Information
>4e7l Chain A (length=365) Species: 11963 (Human spumaretrovirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AELDQLLQGHYIKGYPKQYTYFLEDGKVKVSRPEGVKIIPPQSDRQKIVL
QAHNLAHTGREATLLKIANLYWWPNMRKDVVKQLGRCQQCLITNASNKAS
GPILRPDRPQKPFDKFFIDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTK
APSTSATVKSLNVLTSIAIPKVIHSDQGAAFTSSTFAEWAKERGIHLEFS
TPYHPQSSGKVERKNSDIKRLLTKLLVGRPTKWYDLLPVVQLALNNTYSP
VLKYTPHQLLFGIDSNTPFANQDTLDLTREEELSLLQEIRTSLYHPSTPP
ASSRSWSPVVGQLVQERVARPASLRPRWHKPSTVLKVLNPRTVVILDHLG
NNRTVSIDNLKPTSH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4e7l 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo.
Resolution3.0001 Å
Binding residue
(original residue number in PDB)		D185 Q186 G187 Y212 R362
Binding residue
(residue number reindexed from 1)		D176 Q177 G178 Y203 R353
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:4e7l, PDBe:4e7l, PDBj:4e7l
PDBsum4e7l
PubMed22580823
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

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