Structure of PDB 3zq6 Chain A Binding Site BS03

Receptor Information
>3zq6 Chain A (length=300) Species: 145262 (Methanothermobacter thermautotrophicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFKDLFKFNKGKTTFVFIGGKGGVGKTTISAATALWMARSGKKTLVISTD
PAHSLSDSLEREIGHTPTKITENLYAVEIDPEVAMEEYQAKLASMSPGID
EAAAFDQFLRYMTTDEYDIVIFDTAPTGHTLRLLSFPEIMDSWVGKMIKI
RRQIGSMAKAFKNILPFMGDEEEEDRALQDMEATKKQINAAREVMSDPER
TSFKMVVIPEEMSIYESERAMKALEKYSIHADGVIVNQVLPEESDCEFCN
ARRKLQQERLKQIREKFSDKVVAEVPLLKKEAKGIETLEKIAEQLYGEPE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3zq6 Chain A Residue 1323 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3zq6 A Conserved Archaeal Pathway for Tail-Anchored Membrane Protein Insertion.
Resolution2.107 Å
Binding residue
(original residue number in PDB)		C268 C271
Binding residue
(residue number reindexed from 1)		C246 C249
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G24 G26 K27 T28 T29 D51
Catalytic site (residue number reindexed from 1) G23 G25 K26 T27 T28 D50
Enzyme Commision number 7.3.2.7: arsenite-transporting ATPase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015446 ATPase-coupled arsenite transmembrane transporter activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0046685 response to arsenic-containing substance
GO:0071722 detoxification of arsenic-containing substance

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Molecular Function
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Biological Process
External links
PDB RCSB:3zq6, PDBe:3zq6, PDBj:3zq6
PDBsum3zq6
PubMed21658170
UniProtO27555|ARSA_METTH Putative arsenical pump-driving ATPase (Gene Name=MTH_1511)

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