Structure of PDB 3zd7 Chain A Binding Site BS03

Receptor Information
>3zd7 Chain A (length=623) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLYSPFKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKF
PQGQKGKVVFFANQIPVYEQNKSVFSKYFERHGYRVTGISGATAVPVEQI
VENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIM
FNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNTDEALDYICKLCASLDAS
VIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAK
RICKDLENLSQSQNREFGTQKYEQWIVTVQKACMSRICKALFLYTSHLRK
YNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQEL
ESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWI
EGNPKLSFLKPGILTNILILTSVADEGIDIAQCNLVILYEYVGNARGSKC
FLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEK
FIRDSKENKKLLCRKCKALACYTADVRVIEDCHYTVLGDAFKECFVSRPH
PKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDT
GVQTLYSKWKDFHFEKIPFDPAE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3zd7 Chain A Residue 927 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3zd7 Defining the Functional Determinants for RNA Surveillance by Rig-I.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		C810 C864 C869
Binding residue
(residue number reindexed from 1)		C513 C567 C572
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:3zd7, PDBe:3zd7, PDBj:3zd7
PDBsum3zd7
PubMed23897087
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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