Structure of PDB 3vpb Chain A Binding Site BS03

Receptor Information

>3vpb Chain A (length=281) Species: 273063 (Sulfurisphaera tokodaii str. 7)

MRVVLIVDIVRQEEKLIAKALEENKVQYDIINVAQEPLPFNKALGRYDVA
IIRPVSMYRALYSSAVLEAAGVHTINSSDVINVCGDKILTYSKLYREGIP
IPDSIIALSAEAALKAYEQRGFPLIDKPPIGSWGRLVSLIRDVFEGKTII
EHRELMGNSALKAHIVQEYIQYKGRDIRCIAIGEELLGCYARNIPPNEWR
ANVALGGTPSNIEVDEKLKETVVKAVSIVHGEFVSIDILEHPNKGYVVNE
LNDVPEFKGFMVATNINVAQKLVEYIKENYS

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3vpb Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3vpb Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus
• Resolution: 1.8 Å
• Binding residue (original residue number in PDB): D237 E250
• Binding residue (residue number reindexed from 1): D237 E250
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 6.3.2.-

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0005524 ATP binding
• GO:0016874 ligase activity
• GO:0042802 identical protein binding
• GO:0043774 coenzyme F420-2 alpha-glutamyl ligase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006526 L-arginine biosynthetic process
• GO:0009085 lysine biosynthetic process
• GO:0036211 protein modification process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3vpb, PDBe:3vpb, PDBj:3vpb
• PDBsum: 3vpb
• PubMed: 23434852
• UniProt: Q970U6|ARGX_SULTO Glutamate--LysW ligase ArgX (Gene Name=argX)