Structure of PDB 3ugx Chain A Binding Site BS03

Receptor Information
>3ugx Chain A (length=369) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVY
VSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLI
KKLGANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTD
VEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVS
LSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKT
VAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLAS
STIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHP
QPEDDENFVFEEFARQNLK
Ligand information
Ligand IDPTD
InChIInChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
InChIKeySXRSQZLOMIGNAQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC=O)CC=O
ACDLabs 10.04
CACTVS 3.341		O=CCCCC=O
FormulaC5 H8 O2
NamePENTANEDIAL
ChEMBLCHEMBL1235482
DrugBankDB03266
ZINCZINC000001729593
PDB chain3ugx Chain A Residue 407 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ugx Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin.
Resolution2.649 Å
Binding residue
(original residue number in PDB)		Y250 S252
Binding residue
(residue number reindexed from 1)		Y242 S244
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001664 G protein-coupled receptor binding
Biological Process
GO:0002031 G protein-coupled receptor internalization
GO:0007165 signal transduction
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005829 cytosol
GO:0016020 membrane
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ugx, PDBe:3ugx, PDBj:3ugx
PDBsum3ugx
PubMed22306737
UniProtP08168|ARRS_BOVIN S-arrestin (Gene Name=SAG)

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