Structure of PDB 3ugi Chain A Binding Site BS03

Receptor Information
>3ugi Chain A (length=65) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSRRASVGSHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHK
CREKVANLCEFIVTD
Ligand information
Ligand ID09U
InChIInChI=1S/C5H10O/c1-6-4-5-2-3-5/h5H,2-4H2,1H3
InChIKeyXZUHEKNCBBQEBT-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370
OpenEye OEToolkits 1.7.6		COCC1CC1
ether
FormulaC5 H10 O
Name(methoxymethyl)cyclopropane
ChEMBL
DrugBank
ZINCZINC000080866062
PDB chain3ugi Chain A Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ugi Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Resolution1.361 Å
Binding residue
(original residue number in PDB)		Y236 Y238 M239
Binding residue
(residue number reindexed from 1)		Y15 Y17 M18
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
2.7.11.13: protein kinase C.
External links
PDB RCSB:3ugi, PDBe:3ugi, PDBj:3ugi
PDBsum3ugi
PubMed23283232
UniProtP28867|KPCD_MOUSE Protein kinase C delta type (Gene Name=Prkcd)

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