Structure of PDB 3p65 Chain A Binding Site BS03

Receptor Information

>3p65 Chain A (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

Ligand information

• Ligand ID: AU3
• InChI: InChI=1S/Au/q+3
• InChIKey: CBMIPXHVOVTTTL-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Au+3]
• Formula: Au
• Name: GOLD 3+ ION
• PDB chain: 3p65 Chain A Residue 310

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3p65 Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.
• Resolution: 2.1 Å
• Binding residue (original residue number in PDB): S60 C64 S72 R73
• Binding residue (residue number reindexed from 1): S60 C64 S72 R73
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E35 N46 D48 S50 D52 N59
• Catalytic site (residue number reindexed from 1): E35 N46 D48 S50 D52 N59
• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:3p65, PDBe:3p65, PDBj:3p65
• PDBsum: 3p65
• PubMed: 21278750
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)