Structure of PDB 3mlo Chain A Binding Site BS03

Receptor Information
>3mlo Chain A (length=212) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEI
ERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSM
TKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIID
RFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFV
HNNSKHGENLYF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3mlo Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3mlo Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Resolution3.01 Å
Binding residue
(original residue number in PDB)		H157 C161 C164 C170
Binding residue
(residue number reindexed from 1)		H123 C127 C130 C136
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3mlo, PDBe:3mlo, PDBj:3mlo
PDBsum3mlo
PubMed20876732
UniProtQ07802|COE1_MOUSE Transcription factor COE1 (Gene Name=Ebf1)

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