Structure of PDB 3e0f Chain A Binding Site BS03

Receptor Information

>3e0f Chain A (length=286) Species: 367928 (Bifidobacterium adolescentis ATCC 15703) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EPPAQGWDIHCHTVFSDGTETPRTLVEQARKLGLHGVAIADHDTTAGWDE
ATEASEEIGLPLLLGTEITAVDEDVSVHMLAFQYDPSNEHISSMFANTRA
ARLRRTKRMVERLSQDFPITWDDVLAQVKEGERTTIGRPHIADALVAAGV
YETRSDAFADAVSAKSKYYIPTPSPSTHEVIAAVKGAGGVVVAAHAGDPQ
RNRRLLSDEQLDAMIADGLDGLEVWHRGNPPEQRERLLTIAARHDLLVTG
GSDWHGKGKPNGLGENLTDDDTVREILCRGVDLIGR

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

3e0f Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	3e0f Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	H17 H19 E74 D260
Binding residue (residue number reindexed from 1)	H10 H12 E67 D253
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003824	catalytic activity
GO:0004534	5'-3' RNA exonuclease activity
GO:0035312	5'-3' DNA exonuclease activity
GO:0046872	metal ion binding

	Biological Process
GO:0006259	DNA metabolic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:3e0f, PDBe:3e0f, PDBj:3e0f
PDBsum	3e0f
PubMed	21538547
UniProt	A1A2L3

[Back to BioLiP]