Structure of PDB 3cfx Chain A Binding Site BS03

Receptor Information
>3cfx Chain A (length=293) Species: 2214 (Methanosarcina acetivorans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEVLTVFHAGSLSVPFEELEAEFEAQHPGVDVQREAAGSAQSVRKITELG
KKADVLASADYALIPSLMVPEYADWYAAFARNQMILAYTNESKYGDEINT
DNWYEILRRPDVRYGFSNPNDDPAGYRSQMVTQLAESYYNDDMIYDDLML
ANTGMTLTTEENGTALIHVPASEEISPNTSKIMLRSMEVELSSALETGEI
DYLYIYRSVAEQHGFEYVALPPAIDLSSLEYADNYSKVQVEMVNGEVVTG
SPIVYGVTIPNNAENSELATEFVALLLGETGQQIFIENGQPPI
Ligand information
Ligand IDWO4
InChIInChI=1S/4O.W/q;;2*-1;
InChIKeyPBYZMCDFOULPGH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-][W](=O)(=O)[O-]
ACDLabs 10.04
CACTVS 3.341		[O-][W]([O-])(=O)=O
FormulaO4 W
NameTUNGSTATE(VI)ION
ChEMBL
DrugBank
ZINC
PDB chain3cfx Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3cfx Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		A48 G49 S50 G77 S78 A98 D161 P162 A163 E227 Y245
Binding residue
(residue number reindexed from 1)		A9 G10 S11 G38 S39 A59 D122 P123 A124 E188 Y206
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:1901359 tungstate binding

View graph for
Molecular Function
External links
PDB RCSB:3cfx, PDBe:3cfx, PDBj:3cfx
PDBsum3cfx
PubMed19234723
UniProtQ8TTZ5|Y280_METAC Uncharacterized solute-binding protein MA_0280 (Gene Name=MA_0280)

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