Structure of PDB 2vas Chain A Binding Site BS03

Receptor Information
>2vas Chain A (length=732) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEE
DSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDI
PKIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGES
GAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNS
SRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCA
GASEDIRERLHLSSPDNFRYLNPLLDDHGDFIRMCTAMKKIGLDDEEKLD
LFRVVAGVLHLGNIDFSTQALEYCAELLGLDQDDLRVSLTTRPLKVEQAN
NARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNS
FEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDL
IEARLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSKLAI
HRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFI
RELFESFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGA
QILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPDKLARLDPRL
FCKALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKR
VNHWLICSRWKKVQWCSLSVIKLKNKIKYRAE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2vas Chain A Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2vas The Post-Rigor Structure of Myosin Vi and Implications for the Recovery Stroke.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		T158 S204
Binding residue
(residue number reindexed from 1)		T155 S201
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) S153 G154 T158 N200 S203 S204 G459 E461
Catalytic site (residue number reindexed from 1) S150 G151 T155 N197 S200 S201 G392 E394
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2vas, PDBe:2vas, PDBj:2vas
PDBsum2vas
PubMed18046460
UniProtQ29122|MYO6_PIG Unconventional myosin-VI (Gene Name=MYO6)

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