Structure of PDB 2oyq Chain A Binding Site BS03

Receptor Information
>2oyq Chain A (length=848) Species: 12353 (Escherichia phage RB69) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF
DIYGKPCTRKLFANMRDASQWIKRMEDIGLEALGMDDFKLAYLSDTYNYE
IKYDHTKIRVANFDIEVTSPDGFPEPSQAKHPIDAITHYDSIDDRFYVFD
LLNSPYGNVEEWSIEIAAKLQEQGGDEVPSEIIDKIIYMPFDNEKELLME
YLNFWQQKTPVILTGWNVESFAIPYVYNRIKNIFGESTAKRLSPHRKTRV
KVIENMYGSREIITLFGISVLDYIDLYKKFSFTNQPSYSLDYISEFELNV
GKLKYDGPISKLRESNHQRYISYNIIAVYRVLQIDAKRQFINLSLDMGYY
AKIQIQSVFSPIKTWDAIIFNSLKEQNKVIPQGRSHPVQPYPGAFVKEPI
PNRYKYVMSFDLTSLYPSIIRQVNISPETIAGTFKVAPLHDYINAVAERP
SDVYSCSPNGMMYYKDRDGVVPTEITKVFNQRKEHKGYMLARTEVAGMTA
QINRKLLINSLYGALGNVWFRYYDLRNATAITTFGQMALQWIERKVNEYL
NEVCGTEGEAFVLYGDTDSIYVSADKIIDKVGESKFRDTNHWVDFLDKFA
RERMEPAIDRGFREMCEYMNNKQHLMFMDREAIAGPPLGSKGIGGFWTGK
KRYALNVWDMEGTRYAEPKLKIMGLETQKSSTPKAVQKALKECIRRMLQE
GEESLQEYFKEFEKEFRQLNYISIASVSSANNIAKYDVGGFPGPKCPFHI
RGILTYNRAIKGNIDAPQVVEGEKVYVLPLREGNPFGDKCIAWPSGTEIT
DLIKDDVLHWMDYTVLLEKTFIKPLEGFTSAAKLDYEKKASLFDMFDF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2oyq Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		S36 F38 K48 Y49 R59 G84 M85 D95 F370 K374 K378 V379 I380
Binding residue
(residue number reindexed from 1)		S36 F38 K48 Y49 R59 G84 M85 D95 F370 K374 K378 V379 I380
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2oyq, PDBe:2oyq, PDBj:2oyq
PDBsum2oyq
PubMed17718515
UniProtQ38087|DPOL_BPR69 DNA-directed DNA polymerase (Gene Name=43)

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