Structure of PDB 2ju0 Chain A Binding Site BS03

Receptor Information

>2ju0 Chain A (length=175) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIY
KQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS
WAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI
FKLMDKNEDGYITLDEFREGSKVDP

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

2ju0 Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2ju0 Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1).
Resolution	N/A
Binding residue (original residue number in PDB)	D157 N159 D161 Y163 I164 E168
Binding residue (residue number reindexed from 1)	D155 N157 D159 Y161 I162 E166
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008047	enzyme activator activity
GO:0046872	metal ion binding

	Biological Process
GO:0009966	regulation of signal transduction

	Cellular Component
GO:0000139	Golgi membrane
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0033101	cellular bud membrane
GO:0043231	intracellular membrane-bounded organelle

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External links

PDB	RCSB:2ju0, PDBe:2ju0, PDBj:2ju0
PDBsum	2ju0
PubMed	17720810
UniProt	Q06389\|NCS1_YEAST Calcium-binding protein NCS-1 (Gene Name=FRQ1)

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