Structure of PDB 2ivh Chain A Binding Site BS03

Receptor Information
>2ivh Chain A (length=124) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKK
FWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHQEKP
ISVYDMDNISVVTPKRHIDIHRGK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2ivh Chain A Residue 1577 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ivh Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H544 H569 H573
Binding residue
(residue number reindexed from 1)		H96 H117 H121
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) R538 E542 H544 Q545 H569 H573
Catalytic site (residue number reindexed from 1) R90 E94 H96 Q97 H117 H121
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005102 signaling receptor binding
Biological Process
GO:0009617 response to bacterium
GO:0019835 cytolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2ivh, PDBe:2ivh, PDBj:2ivh
PDBsum2ivh
PubMed17175542
UniProtQ47112|CEA7_ECOLX Colicin-E7 (Gene Name=colE7)

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