Structure of PDB 2hvr Chain A Binding Site BS03

Receptor Information
>2hvr Chain A (length=319) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMFKKYSSLENHYNSKFIEKLYSLGLTGGEWVAREKIHGTNFSLIIERDK
VTCAKRTGPILPAEDFFGYEIILKNYADSIKAVQDIMETSAVVSYQVFGE
FAGPGIQKNVDYGDKDFYVFDIIVTTESGDVTYVDDYMMESFCNTFKFKM
APLLGRGKFEELIKLPNDLDSVVQDYNFTVDHAGLVDANKCVWNAEAKGE
VFTAEGYVLKPCYPSWLRNGNRVAIKCKNSKFELSEADNKLVGILACYVT
LNRVNNVISKIGEIGPKDFGKVMGLTVQDILEETSREGITLTQADNPSLI
KKELVKMVQDVLRPAWIEL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2hvr RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		Y5 K35 I36 N40 R55 E99 F119 V207 K225 K227
Binding residue
(residue number reindexed from 1)		Y6 K36 I37 N41 R56 E100 F120 V208 K226 K228
Enzymatic activity
Enzyme Commision number 6.5.1.3: RNA ligase (ATP).
Gene Ontology
Molecular Function
GO:0003972 RNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0042245 RNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2hvr, PDBe:2hvr, PDBj:2hvr
PDBsum2hvr
PubMed17018278
UniProtP32277|RLIG2_BPT4 RNA ligase 2 (Gene Name=Y10A)

[Back to BioLiP]