Structure of PDB 2ezv Chain A Binding Site BS03

Receptor Information
>2ezv Chain A (length=267) Species: 68197 (Streptomyces fimbriatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MHQDYRELSLDELESVEKQTLRTIVQALQQYSKEAKSIFETTAADSSGEV
IVLAEDITQYALEVAETYPINRRFAGFIDYKRVRWLPSPHGLLPQVLLVD
AKASTEKNRDTLQRSQLPMDAEFRNTSSGEVVTMEAGVIPHLMLQSANDG
VLPAVTTSIFVHFYYRELKEGRYRELKSIYVLSLPHARLKQRYNPDPDTS
FFGAGKHSPARGEVARIRVYFDRLKEACPWRLQELHYSADSEYTQPRWRD
LNDAGHEVTKEFLFLER
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2ezv Chain A Residue 270 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ezv A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D79 D100 A101
Binding residue
(residue number reindexed from 1)		D79 D100 A101
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:2ezv, PDBe:2ezv, PDBj:2ezv
PDBsum2ezv
PubMed16308566
UniProtO52512|T2S1_STRFI Type II restriction enzyme SfiI (Gene Name=sfiIR)

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