Structure of PDB 2ex5 Chain A Binding Site BS03

Receptor Information
>2ex5 Chain A (length=207) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ILKPGEKLPQDKLEELKKINDAVKKTKNFSKYLIDLRKLFQIDEVQVTSE
SKLFLAGFLEGEASLNISTKKLATSKFGLVVDPEFNVTRHVNGVKVLYLA
LEVFKTGRIRHKSGSNATLVLTIDNRQSLEEKVIPFYEQYVVAFSSPEKV
KRVANFKALLELFNNDAHQDLEQLVNKILPIWDQMRKQQGQSNEGFPNLE
AAQDFAR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2ex5 Chain X Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ex5 The structure of I-CeuI homing endonuclease: Evolving asymmetric DNA recognition from a symmetric protein scaffold.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		G65 E66
Binding residue
(residue number reindexed from 1)		G61 E62
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006314 intron homing
Cellular Component
GO:0005739 mitochondrion
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ex5, PDBe:2ex5, PDBj:2ex5
PDBsum2ex5
PubMed16698548
UniProtP32761|DNE1_CHLMO DNA endonuclease I-CeuI

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