Structure of PDB 2byo Chain A Binding Site BS03

Receptor Information

>2byo Chain A (length=183) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SDPALLAEIRQSLDATKGLTSVHVAVRTTGKVDSLLGITSADVDVRANPL
AAKGVCTYNDEQGVPFRVQGDNISVKLFDDWSNLGSISELSTSRVGVTQL
LSGVTNLQAQGTEVIDGISTTKITGTIPASSVKMLDPGAKSARPATVWIA
QDGSHHLVRASIDLGSGSIQLTQSKWNEPVNVD

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

2byo Chain A Residue 1213 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2byo Lppx is a Lipoprotein Required for the Translocation of Phthiocerol Dimycocerosates to the Surface of Mycobacterium Tuberculosis.
Resolution	2.15 Å
Binding residue (original residue number in PDB)	H42 D63
Binding residue (residue number reindexed from 1)	H23 D44
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005319	lipid transporter activity

	Biological Process
GO:0006869	lipid transport
GO:0071770	DIM/DIP cell wall layer assembly

	Cellular Component
GO:0005576	extracellular region
GO:0005886	plasma membrane
GO:0009274	peptidoglycan-based cell wall
GO:0009986	cell surface

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Cellular Component

External links

PDB	RCSB:2byo, PDBe:2byo, PDBj:2byo
PDBsum	2byo
PubMed	16541102
UniProt	P9WK65\|LPPX_MYCTU Putative phthiocerol dimycocerosate transporter LppX (Gene Name=lppX)

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