Structure of PDB 2bgw Chain A Binding Site BS03

Receptor Information
>2bgw Chain A (length=219) Species: 56636 (Aeropyrum pernix) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLEDPGGRPRVYVDVREERSPVPSILESLGVQVIPKQLPMGDYLVSDSII
VERKTSSDFAKSLFDGRLFEQASRLAEHYETVFIIVEGPPVPRRYRGRER
SLYAAMAALQLDYGIRLMNTMDPKGTALVIESLARLSTREGGQRIVIHKK
PRLSDVREWQLYILQSFPGIGRRTAERILERFGSLERFFTASKAEISKVE
GIGEKRAEEIKKILMTPYK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2bgw Chain A Residue 1230 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2bgw Structure of an XPF endonuclease with and without DNA suggests a model for substrate recognition.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D52 E62 R63
Binding residue
(residue number reindexed from 1)		D42 E52 R53
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004518 nuclease activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2bgw, PDBe:2bgw, PDBj:2bgw
PDBsum2bgw
PubMed15719018
UniProtQ9YC15

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