Structure of PDB 2aq4 Chain A Binding Site BS03

Receptor Information
>2aq4 Chain A (length=428) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKD
TYIIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCN
YVARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKR
LNIFNLILPISIDEAVCVRIIPDTLNARLCEEIRQEIFQGTNGCTVSIGC
SDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHSTLSR
LESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEESLKI
LYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNEINKT
TSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGIIATE
MKSLYRTLGCPPMELRGLALQFNKLVDV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2aq4 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2aq4 Rev1 employs a novel mechanism of DNA synthesis using a protein template.
Resolution2.32 Å
Binding residue
(original residue number in PDB)		D362 D467 E468
Binding residue
(residue number reindexed from 1)		D58 D163 E164
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2aq4, PDBe:2aq4, PDBj:2aq4
PDBsum2aq4
PubMed16195463
UniProtP12689|REV1_YEAST DNA repair protein REV1 (Gene Name=REV1)

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