Structure of PDB 1xig Chain A Binding Site BS03
Receptor Information
>1xig Chain A (length=385) Species:
1929
(Streptomyces rubiginosus) [
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YQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVQRLAELGAHGVT
FHDDDLIPFGSSDSEREEHVKRFRQALDDTGMKVPMATTNLFTHPVFKDG
GFTANDRDVRRYALRKTIRNIDLAVELGAETYVAWGGREGAESGGAKDVR
DALDRMKEAFDLLGEYVTSQGYDIRFAIEPKPNEPRGDILLPTVGHALAF
IERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQNGI
KYDQDLRFGAGDLRAAFWLVDLLESAGYSGPRHFDFKPPRTEDFDGVWAS
AAGCMRNYLILKERAAAFRADPEVQEALRASRLDELARPTAADGLQALLD
DRSAFEEFDVDAAAARGMAFERLDQLAMDHLLGAR
Ligand information
Ligand ID
MN
InChI
InChI=1S/Mn/q+2
InChIKey
WAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mn+2]
CACTVS 3.341
[Mn++]
Formula
Mn
Name
MANGANESE (II) ION
ChEMBL
DrugBank
DB06757
ZINC
PDB chain
1xig Chain A Residue 391 [
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Receptor-Ligand Complex Structure
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PDB
1xig
Modes of binding substrates and their analogues to the enzyme D-xylose isomerase.
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
E181 E217 D245 D287
Binding residue
(residue number reindexed from 1)
E179 E215 D243 D285
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
H54 D57 M88 E181 K183 E217 H220 D245 D255 D257 D287
Catalytic site (residue number reindexed from 1)
H52 D55 M86 E179 K181 E215 H218 D243 D253 D255 D285
Enzyme Commision number
5.3.1.5
: xylose isomerase.
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0009045
xylose isomerase activity
GO:0016853
isomerase activity
GO:0042802
identical protein binding
GO:0046872
metal ion binding
Biological Process
GO:0005975
carbohydrate metabolic process
GO:0042732
D-xylose metabolic process
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1xig
,
PDBe:1xig
,
PDBj:1xig
PDBsum
1xig
PubMed
15299449
UniProt
P24300
|XYLA_STRRU Xylose isomerase (Gene Name=xylA)
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