Structure of PDB 1sl8 Chain A Binding Site BS03

Receptor Information
>1sl8 Chain A (length=181) Species: 6100 (Aequorea victoria) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPKWIGRHKHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRH
KDAVEAFFGGAGMKYGVETEWPEYIEGWKRLASEELKRYSKNQITLIRLW
GDALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRVCDIDESG
QLDVDEMTRQHLGFWYTMDPACEKLYGGAVP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1sl8 Chain A Residue 671 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1sl8 All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D119 D121 N123 A125 E130
Binding residue
(residue number reindexed from 1)		D109 D111 N113 A115 E120
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H18 W88 Y134 H171 Y186
Catalytic site (residue number reindexed from 1) H8 W78 Y124 H161 Y176
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0008218 bioluminescence

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Molecular Function
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Biological Process
External links
PDB RCSB:1sl8, PDBe:1sl8, PDBj:1sl8
PDBsum1sl8
PubMed15689515
UniProtP07164|AEQ1_AEQVI Aequorin-1

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