Structure of PDB 1sl6 Chain A Binding Site BS03

Receptor Information
>1sl6 Chain A (length=168) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEKSKLQEIYQELTQLKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNC
YFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMG
LSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDN
RCDVDNYWICKKPAACFR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1sl6 Chain A Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1sl6 Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Resolution2.25 Å
Binding residue
(original residue number in PDB)		E359 N361 E366 N377 D378
Binding residue
(residue number reindexed from 1)		E130 N132 E137 N148 D149
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1sl6, PDBe:1sl6, PDBj:1sl6
PDBsum1sl6
PubMed15195147
UniProtQ9H2X3|CLC4M_HUMAN C-type lectin domain family 4 member M (Gene Name=CLEC4M)

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