Structure of PDB 1rgo Chain A Binding Site BS03

Receptor Information
>1rgo Chain A (length=70) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTF
HTIGFCPYGPRCHFIHNADE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1rgo Chain A Residue 222 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1rgo Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d.
ResolutionN/A
Binding residue
(original residue number in PDB)		C197 C206 C212 H216
Binding residue
(residue number reindexed from 1)		C47 C56 C62 H66
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1rgo, PDBe:1rgo, PDBj:1rgo
PDBsum1rgo
PubMed14981510
UniProtP47974|TISD_HUMAN mRNA decay activator protein ZFP36L2 (Gene Name=ZFP36L2)

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