Structure of PDB 1r6n Chain A Binding Site BS03

Receptor Information
>1r6n Chain A (length=196) Species: 10580 (human papillomavirus 11) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HEAIAKRLDACQDQLLELYEENSIDIHKHIMHWKCIRLESVLLHKAKQMG
LSHIGLQVVPPLTVSETKGHNAIEMQMHLESLAKTQYGVEPWTLQDTSYE
MWLTPPKRCFKKQGNTVEVKFDGCEDNVMEYVVWTHIYLQDNDSWVKVTS
SVDAKGIYYTCGQFKTYYVNFNKEAQKYGSTNHWEVCYGSTVICSP
Ligand information
Ligand IDALQ
InChIInChI=1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6)
InChIKeyKQNPFQTWMSNSAP-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370CC(C)C(O)=O
OpenEye OEToolkits 1.7.0CC(C)C(=O)O
ACDLabs 12.01O=C(O)C(C)C
FormulaC4 H8 O2
Name2-METHYL-PROPIONIC ACID
ChEMBLCHEMBL108778
DrugBankDB02531
ZINCZINC000000901420
PDB chain1r6n Chain A Residue 1113 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1r6n Crystal Structure of the E2 Transactivation Domain of Human Papillomavirus Type 11 Bound to a Protein Interaction Inhibitor
Resolution2.4 Å
Binding residue
(original residue number in PDB)		L15 L16 H32
Binding residue
(residue number reindexed from 1)		L15 L16 H32
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006275 regulation of DNA replication
GO:0006355 regulation of DNA-templated transcription
GO:0016032 viral process

View graph for
Biological Process
External links
PDB RCSB:1r6n, PDBe:1r6n, PDBj:1r6n
PDBsum1r6n
PubMed14634007
UniProtP04015|VE2_HPV11 Regulatory protein E2 (Gene Name=E2)

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