Structure of PDB 1r0o Chain A Binding Site BS03

Receptor Information
>1r0o Chain A (length=76) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKR
QRNRCQYCRYQKCLTCGMKREAVQEE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1r0o Chain A Residue 351 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1r0o Structure of the Heterodimeric Ecdysone Receptor DNA-binding Complex
Resolution2.24 Å
Binding residue
(original residue number in PDB)		C7 C10 C24 C27
Binding residue
(residue number reindexed from 1)		C3 C6 C20 C23
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1r0o, PDBe:1r0o, PDBj:1r0o
PDBsum1r0o
PubMed14592980
UniProtP20153|USP_DROME Protein ultraspiracle (Gene Name=usp)

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