Structure of PDB 1qfc Chain A Binding Site BS03

Receptor Information
>1qfc Chain A (length=287) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAPASTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQIMGADFIMSL
GDNFYFTGVHDANDKRFQETFEDVFSDRALRNIPWYVLAGNHDHLGNVSA
QIAYSKISKRWNFPSPYYRLRFKVPRSNITVAIFMLDTVMLCGNSVARTQ
LSWLKKQLAAAKEDYVLVAGHYPIWSIAEHGPTRCLVKNLRPLLAAYGVT
AYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSVRHQRKVPNGYLRFHYG
SEDSLGGFTYVEIGSKEMSITYVEASGKSLFKTSLPR
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain1qfc Chain A Residue 410 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1qfc Crystal structure of a mammalian purple acid phosphatase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		N91 H92 H195 H221 H223
Binding residue
(residue number reindexed from 1)		N91 H92 H180 H206 H208
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.2: acid phosphatase.
Gene Ontology
Molecular Function
GO:0003993 acid phosphatase activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:1qfc, PDBe:1qfc, PDBj:1qfc
PDBsum1qfc
PubMed10388567
UniProtP29288|PPA5_RAT Tartrate-resistant acid phosphatase type 5 (Gene Name=Acp5)

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