Structure of PDB 1p4e Chain A Binding Site BS03

Receptor Information
>1p4e Chain A (length=400) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQFDILCKTPPKVLVRQFVERFERPSGEKIASCAAELTYLCWMITHNGTA
IKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWE
FTIIPYNGQSDITDIVSSLQLQFESGNSHSKKMLKALLSEGESIWEITEK
ILNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNKY
LGVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLDEFLRNSEPVLKRVN
RTGNSSSNKQEYQLLKDNLVRSYNKALKKNAPYPIFAIKNGPKSHIGRHL
MTSFLSMKGLTELTNVVGNFSDKQITAIPDHYFALVSRYYAYDPISKEMI
ALKDETNPIEEWQHIEQLKGSAEGSIRYPAWNGIISQEVLDYLSSYINRR
Ligand information
Receptor-Ligand Complex Structure
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PDB1p4e The role of the conserved Trp330 in Flp-mediated recombination. Functional and structural analysis
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H47 K53 A55 T56 Y60 K82 N108 F192 S193 K223 R281 N284 K299 N300 G301 K303 S304 H305
Binding residue
(residue number reindexed from 1)		H46 K52 A54 T55 Y59 K81 N107 F182 S183 K213 R271 N274 K289 N290 G291 K293 S294 H295
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0008301 DNA binding, bending
GO:0009009 site-specific recombinase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0042150 plasmid recombination
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1p4e, PDBe:1p4e, PDBj:1p4e
PDBsum1p4e
PubMed12716882
UniProtP03870|FLP_YEAST Site-specific recombinase Flp (Gene Name=FLP1)

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