Structure of PDB 1oxy Chain A Binding Site BS03

Receptor Information
>1oxy Chain A (length=573) Species: 6850 (Limulus polyphemus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLHDKQIRICHLFEQLSRLKNVGKLQPGAIFSCFHPDHLEEARHLYEVFW
EAGDFNDFIEIAKEARTFVNEGLFAFAAEVAVLHRDDCKGLYVPPVQEIF
PDKFIPSAAINEAFKKGNILDPEYRLAYYREDVGINAHHWHWHLVYPSTW
NPKYFGKKKDRKGELFYYMHQQMCARYDCERLSNGMHRMLPFNNFDEPLA
GYAPHLTHVASGKYYSPRPDGLKLRDLGDIEISEMVRMRERILDSIHLGY
VISEDGSHKTLDELHGTDILGALVESSYESVNHEYYGNLHNWGHVTMARI
HDPDGRFHEEPGVMSDTSTSLRDPIFYNWHRFIDNIFHEYKNTLKPYDHD
VLNFPDIQVQDVTLHARVDNVVHTFMREQELELKHGSIKAKYYHLDHEPF
SYAVNVQNNSASDKHATVRIFLAPKYDELGNEIKADELRRTAIELDKFKT
DLHPGKNTVVRHSLDSSVTLSHQPTFEDLLSEYCSCGWPSHLLVPKGNVA
GMEYHLFVMLTDWDKDKVDVACVDAVSYCGARDHKYPDKKPMGFPFDRPI
HTEHISDFLTNNMFIKDIKIKFH
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain1oxy Chain A Residue 631 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1oxy Crystallographic analysis of oxygenated and deoxygenated states of arthropod hemocyanin shows unusual differences.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H173 H177 H204 H324 H328
Binding residue
(residue number reindexed from 1)		H139 H143 H170 H290 H294
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005344 oxygen carrier activity
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0031404 chloride ion binding
GO:0046872 metal ion binding
Biological Process
GO:0015671 oxygen transport
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1oxy, PDBe:1oxy, PDBj:1oxy
PDBsum1oxy
PubMed7984626
UniProtP04253|HCY2_LIMPO Hemocyanin II

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