Structure of PDB 1omd Chain A Binding Site BS03

Receptor Information

>1omd Chain A (length=107) Species: 10116 (Rattus norvegicus)

ITDILSAEDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDIFRFID
NDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADE
FQEMVHS

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1omd Chain A Residue 135

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1omd Structure of oncomodulin refined at 1.85 A resolution. An example of extensive molecular aggregation via Ca2+.
• Resolution: 1.85 Å
• Binding residue (original residue number in PDB): Q71 D73
• Binding residue (residue number reindexed from 1): Q70 D72
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005509 calcium ion binding
• GO:0042802 identical protein binding
• GO:0042803 protein homodimerization activity
• GO:0044877 protein-containing complex binding
• GO:0046872 metal ion binding

Biological Process

• GO:0009611 response to wounding
• GO:0090102 cochlea development

Cellular Component

• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0031982 vesicle
• GO:0032420 stereocilium
• GO:0032437 cuticular plate
• GO:0032991 protein-containing complex
• GO:0099512 supramolecular fiber

External links

• PDB: RCSB:1omd, PDBe:1omd, PDBj:1omd
• PDBsum: 1omd
• PubMed: 2231727
• UniProt: P02631|ONCO_RAT Oncomodulin (Gene Name=Ocm)