Structure of PDB 1nl1 Chain A Binding Site BS03

Receptor Information
>1nl1 Chain A (length=147) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANKGFLEEVRKGNLERECLEEPCSREEAFEALESLSATDAFWAKYTACES
ARNPREKLNECLEGNCAEGVGMNYRGNVSVTRSGIECQLWRSRYPHKPEI
NSTTHPGADLRENFCRNPDGSITGPWCYTTSPTLRREECSVPVCGQD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1nl1 Chain A Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1nl1 Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		E8 E17 E27 E30
Binding residue
(residue number reindexed from 1)		E8 E17 E27 E30
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.5: thrombin.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1nl1, PDBe:1nl1, PDBj:1nl1
PDBsum1nl1
PubMed12923575
UniProtP00735|THRB_BOVIN Prothrombin (Gene Name=F2)

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