Structure of PDB 1n6j Chain A Binding Site BS03

Receptor Information
>1n6j Chain A (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSA
NRLFQYASTDMDRVLLKYTEYSEPHESRTNTDILETLKRRGIG
Ligand information
>1n6j Chain G (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SPKGSISEETKQKLKSAILSAQSAAN
Receptor-Ligand Complex Structure
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PDB1n6j Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Q56 D61 D63 L67 Y69 T70 S73 E74 P75
Binding residue
(residue number reindexed from 1)		Q55 D60 D62 L66 Y68 T69 S72 E73 P74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1n6j, PDBe:1n6j, PDBj:1n6j
PDBsum1n6j
PubMed12700764
UniProtQ02080|MEF2B_HUMAN Myocyte-specific enhancer factor 2B (Gene Name=MEF2B)

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