Structure of PDB 1mus Chain A Binding Site BS03

Receptor Information
>1mus Chain A (length=458) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SALHRAADWAKSVFSSAALGDPRRTARLVNVAAQLAKYSGKSITISSEGS
KAAQEGAYRFIRNPNVSAEAIRKAGAMQTVKLAQEFPELLAIEDTTSLSY
RHQVAEELGKLGSIQKASRGWWVHSVLLLEATTFRTVGLLHQEWWMRPDD
PADADEKESGKWLAAAATSRLRMGSMMSNVIAVCDREADIHAYLQDKLAH
NERFVVRSKHPRKDVESGLYLYDHLKNQPELGGYQISIPQKGVVDKRGKR
KNRPARKASLSLRSGRITLKQGNITLNAVLAEEINPPKGETPLKWLLLTS
EPVESLAQALRVIDIYTHRWRIEEFHKAWKTGAGAERQRMEKPDNLERMV
SILSFVAVRLLQLRESFTPPSQSAETVLTPDECQLLGYLDKGKRKRKEKA
GSLQWAYMAIARLGGFMDSKRTGIASWGALWEGWEALQSKLDGFLAAKDL
MAQGIKIG
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain1mus Chain A Residue 478 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1mus Structure/function insights into Tn5 transposition.
Resolution1.9 Å
Binding residue
(original residue number in PDB)
D97 E326
Binding residue
(residue number reindexed from 1)
D94 E323
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004803 transposase activity
GO:0046872 metal ion binding
Biological Process
GO:0006310 DNA recombination
GO:0006313 DNA transposition
GO:0032196 transposition

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1mus, PDBe:1mus, PDBj:1mus
PDBsum1mus
PubMed15102449
UniProtQ46731|TN5P_ECOLX Transposase for transposon Tn5 (Gene Name=tnpA)

[Back to BioLiP]