Structure of PDB 1l7n Chain A Binding Site BS03

Receptor Information
>1l7n Chain A (length=209) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKKKLILFDFDSTLVNNETIDEIAREAGVEEEVKKITKEAMEGKLNFEQS
LRKRVSLLKDLPIEKVEKAIKRITPTEGAEETIKELKNRGYVVAVVSGGF
DIAVNKIKEKLGLDYAFANRLIVKDGKLTGDVEGEVLKENAKGEILEKIA
KIEGINLEDTVAVGDGANDISMFKKAGLKIAFCAKPILKEKADICIEKRD
LREILKYIK
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain1l7n Chain A Residue 219 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1l7n Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D11 F12 D13 S99 K144
Binding residue
(residue number reindexed from 1)		D9 F10 D11 S97 K142
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D11 F12 D13 G100 K144 D171
Catalytic site (residue number reindexed from 1) D9 F10 D11 G98 K142 D169
Enzyme Commision number 3.1.3.3: phosphoserine phosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0036424 L-phosphoserine phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006564 L-serine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1l7n, PDBe:1l7n, PDBj:1l7n
PDBsum1l7n
PubMed12051918
UniProtQ58989|SERB_METJA Phosphoserine phosphatase (Gene Name=MJ1594)

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