Structure of PDB 1ki0 Chain A Binding Site BS03

Receptor Information
>1ki0 Chain A (length=253) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEE
NYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISK
TMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTD
PNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHW
SAQTPHTHERTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKI
PSC
Ligand information
Ligand IDBCN
InChIInChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
InChIKeyFSVCELGFZIQNCK-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CO)N(CCO)CC(=O)O
CACTVS 3.341OCCN(CCO)CC(O)=O
ACDLabs 10.04O=C(O)CN(CCO)CCO
FormulaC6 H13 N O4
NameBICINE
ChEMBL
DrugBankDB03709
ZINCZINC000001683490
PDB chain1ki0 Chain A Residue 337 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ki0 The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		R290 K311 W315 H317 R324 W325
Binding residue
(residue number reindexed from 1)		R210 K231 W235 H237 R244 W245
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
External links
PDB RCSB:1ki0, PDBe:1ki0, PDBj:1ki0
PDBsum1ki0
PubMed12054798
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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