Structure of PDB 1jnf Chain A Binding Site BS03

Receptor Information
>1jnf Chain A (length=674) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKTVRWCAVNDHEASKCANFRDSMKKVLPEDGPRIICVKKASYLDCIKAI
AAHEADAVTLDAGLVHEAGLTPNNLKPVVAEFYGSKENPKTFYYAVALVK
KGSNFQLNELQGKKSCHTGLGRSAGWNIPIGLLLCDLPEPRKPLEKAVAS
FFSGSCVPCADGADFPQLCQLCPGCGCSSVQPYFGYSGAFKCLKDGLGDV
AFVKQETIFENLPSKDERDQYELLCLDNTRKPVDEYEQCHLARVPSHAVV
ARSVDGKEDLIWELLNQAQEHFGKDKSGDFQLFSSPHGKNLLFKDSAYGF
FKVPPRMDANLYLGYEYVTAVRNLREGICPDPLQDECKAVKWCALGHHER
LKCDEWSVTSGGLIECESAETPEDCIAKIMNGEADAMSLDGGYVYIAGQC
GLVPVLAENYESTDCKKAPEEGYLSVAVVKKSNPDINWNNLEGKKSCHTA
VDRTAGWNIPMGLLYNRINHCRFDEFFRQGCAPGSQKNSSLCELCVGPSV
CAPNNREGYYGYTGAFRCLVEKGDVAFVKSQTVLQNTGGRNSEPWAKDLK
EEDFELLCLDGTRKPVSEAHNCHLAKAPNHAVVSRKDKAACVKQKLLDLQ
VEFGNTVADCSSKFCMFHSKTKDLLFRDDTKCLVDLRGKNTYEKYLGADY
IKAVSNLRKCSTSRLLEACTFHKH
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1jnf Chain A Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1jnf The crystal and molecular structures of diferric porcine and rabbit serum transferrins at resolutions of 2.15 and 2.60 A, respectively.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		D63 Y95 Y188 H249
Binding residue
(residue number reindexed from 1)		D61 Y93 Y186 H247
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0019731 antibacterial humoral response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0055037 recycling endosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1jnf, PDBe:1jnf, PDBj:1jnf
PDBsum1jnf
PubMed11752780
UniProtP19134|TRFE_RABIT Serotransferrin (Gene Name=TF)

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