Structure of PDB 1iuc Chain A Binding Site BS03

Receptor Information
>1iuc Chain A (length=312) Species: 5188 (Aleuria aurantia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTEFLYTSKIAAISWAATGGRQQRVYFQDLNGKIREAQRGGDNPWTGGSS
QNVIGEAKLFSPLAAVTWKSAQGIQIRVYCVNKDNILSEFVYDGSKWITG
QLGSVGVKVGSNSKLAALQWGGSESAPPNIRVYYQKSNGSGSSIHEYVWS
GKWTAGASFGSTVPGTGIGATAIGPGRLRIYYQATDNKIREHCWDSNSWY
VGGFSASASAGVSIAAISWGSTPNIRVYWQKGREELYEAAYGGSWNTPGQ
IKDASRPTPSLPDTFIAANSSGNIDISVFFQASGVSLQQWQWISGKGWSI
GAVVPTGTPAGW
Ligand information
Ligand IDFUC
InChIInChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6+/m0/s1
InChIKeySHZGCJCMOBCMKK-SXUWKVJYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)C
OpenEye OEToolkits 1.5.0CC1C(C(C(C(O1)O)O)O)O
OpenEye OEToolkits 1.5.0C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O)O)O)O
CACTVS 3.341C[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
FormulaC6 H12 O5
Namealpha-L-fucopyranose;
alpha-L-fucose;
6-deoxy-alpha-L-galactopyranose;
L-fucose;
fucose
ChEMBLCHEMBL1232862
DrugBankDB04473
ZINCZINC000001532814
PDB chain1iuc Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1iuc Crystal Structure of Fucose-Specific Lectin from Aleuria aurantia Binding Ligands at Three of Its Five Sugar Recognition Sites
Resolution2.24 Å
Binding residue
(original residue number in PDB)		R179 E191 G202 G203 Y241
Binding residue
(residue number reindexed from 1)		R179 E191 G202 G203 Y241
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042806 fucose binding
Biological Process
GO:0030582 reproductive fruiting body development
GO:0050832 defense response to fungus

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1iuc, PDBe:1iuc, PDBj:1iuc
PDBsum1iuc
PubMed14503859
UniProtP18891|LECF_ALEAU Fucose-specific lectin

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