Structure of PDB 1iaw Chain A Binding Site BS03

Receptor Information
>1iaw Chain A (length=304) Species: 68170 (Lentzea aerocolonigenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPDDDLERVRATLYSLDPDGDRTAGVLRDTLDQLYDGQRTGRWNFDQLHK
TEKTHMGTLVEINLHREFQFGDGFETDYEIAGVQVDCKFSMSQGAWMLPP
ESIGHICLVIWASDQQCAWTAGLVKVIPQFLGTANRDLKRRLTPEGRAQV
VKLWPDHGKLQENLLLHIPGDVRDQIFSAKSSRGNQHGQARVNELFRRVH
GRLIGRAVIATVAQQDDFMKRVRGSGGARSILRPEGIIILGHQDNDPKVA
NDLGLPVPRKGQVVAARVVPADEGDQRQTAEIQGRRWAVAVPGDPIVEAP
VVPR
Ligand information
Receptor-Ligand Complex Structure
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PDB1iaw Structure of NaeI-DNA complex reveals dual-mode DNA recognition and complete dimer rearrangement.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K59 T60 T142 N144 R145
Binding residue
(residue number reindexed from 1)		K50 T51 T133 N135 R136
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1iaw, PDBe:1iaw, PDBj:1iaw
PDBsum1iaw
PubMed11473254
UniProtP50187|T2N1_LENAE Type II restriction enzyme NaeI (Gene Name=naeIR)

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