Structure of PDB 1i1a Chain A Binding Site BS03

Receptor Information
>1i1a Chain A (length=265) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPLMYHLAAVSDLSTGLPSFWATGWLGAQQYLTYNNLRQEADPCGAWIWE
NQVSWYWEKETTDLKSKEQLFLEAIRTLENQINGTFTLQGLLGCELAPDN
SSLPTAVFALNGEEFMRFNPRTGNWSGEWPETDIVGNLWMKQPEAARKES
EFLLTSCPERLLGHLERGRQNLEWKEPPSMRLKARPGNSGSSVLTCAAFS
FYPPELKFRFLRNGLASGSGNCSTGPNGDGSFHAWSLLEVKRGDEHHYQC
QVEHEGLAQPLTVDL
Ligand information
Ligand IDCYS
InChIInChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKeyXUJNEKJLAYXESH-REOHCLBHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CS)C(O)=O
OpenEye OEToolkits 1.5.0C([C@@H](C(=O)O)N)S
CACTVS 3.341N[C@@H](CS)C(O)=O
ACDLabs 10.04O=C(O)C(N)CS
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)S
FormulaC3 H7 N O2 S
NameCYSTEINE
ChEMBLCHEMBL863
DrugBankDB00151
ZINCZINC000000895042
PDB chain1i1a Chain A Residue 951 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1i1a Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		L210 C226
Binding residue
(residue number reindexed from 1)		L206 C222
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1i1a, PDBe:1i1a, PDBj:1i1a
PDBsum1i1a
PubMed11336709
UniProtP13599|FCGRN_RAT IgG receptor FcRn large subunit p51 (Gene Name=Fcgrt)

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