Structure of PDB 1gat Chain A Binding Site BS03

Receptor Information
>1gat Chain A (length=60) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRAGTVCSNCQTSTTTLWRRSPMGDPVCNACGLYYKLHQVNRPLTMRKDG
IQTRNRKVSS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1gat Chain A Residue 67 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1gat NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
ResolutionN/A
Binding residue
(original residue number in PDB)
C7 C10 C28 C31
Binding residue
(residue number reindexed from 1)
C7 C10 C28 C31
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:1gat, PDBe:1gat, PDBj:1gat
PDBsum1gat
PubMed8332909
UniProtP17678|GATA1_CHICK Erythroid transcription factor (Gene Name=GATA1)

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