Structure of PDB 1eb7 Chain A Binding Site BS03

Receptor Information

>1eb7 Chain A (length=317) Species: 287 (Pseudomonas aeruginosa)

DALHDQASALFKPIPEQVTELRGQPISEQQRELGKKLFFDPRLSRSHVLS
CNTCHNVGTGGADNVPTSVGHGWQKGPRNSPTVFNAVFNAAQFWDGRAKD
LGEQAKGPIQNSVEMHSTPQLVEQTLGSIPEYVDAFRKAFPKAGKPVSFD
NMALAIEAYEATLVTPDSPFDLYLKGDDKALDAQQKKGLKAFMDSGCSAC
HNGINLGGQAYFPFGLVKKPDADKGRFAVTKTQSDEYVFRAAPLRNVALT
APYFHSGQVWELKDAVAIMGNAQLGKQLAPDDVENIVAFLHSLSGKQPRV
EYPLLPASTETTPRPAE

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1eb7 Chain A Residue 403

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1eb7 Crystal Structure of the Di-Haemcytochrome C Peroxidase from Pseudomonas Aeruginosa
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): N79 T256 P258
• Binding residue (residue number reindexed from 1): N79 T250 P252
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E114
• Catalytic site (residue number reindexed from 1): E114
• Enzyme Commision number: 1.11.1.5: cytochrome-c peroxidase.

Gene Ontology

Molecular Function

• GO:0004130 cytochrome-c peroxidase activity
• GO:0004601 peroxidase activity
• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:1eb7, PDBe:1eb7, PDBj:1eb7
• PDBsum: 1eb7
• PubMed: 8591033
• UniProt: P14532|CCPR_PSEAE Cytochrome c551 peroxidase (Gene Name=ccpA)