Structure of PDB 1ea7 Chain A Binding Site BS03

Receptor Information
>1ea7 Chain A (length=310) Species: 1421 (Lysinibacillus sphaericus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RASQQIPWGIKAIYNNDTLTSTTGGSGINIAVLDTGVNTSHPDLVNNVEQ
CKDFTGATTPINNSCTDRNGHGTHVAGTALADGGSDQAGIYGVAPDADLW
AYKVLLDSGSGYSDDIAAAIRHAADQATATGTKTIISMSLGSSANNSLIS
SAVNYAYSKGVLIVAAAGNSGYSQGTIGYPGALPNAIAVAALENVQQNGT
YRVADYSSRGYISTAGDYVIQEGDIEISAPGSSVYSTWYNGGYNTISGTS
MATPHVSGLAAKIWAENPSLSNTQLRSNLQERAKSVDIKGGYGAAIGDDY
ASGFGFARVQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1ea7 Chain A Residue 313 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1ea7 The 0.93A Crystal Structure of Sphericase: A Calcium-Loaded Serine Protease from Bacillus Sphaericus
Resolution0.93 Å
Binding residue
(original residue number in PDB)		N29 E49 D98
Binding residue
(residue number reindexed from 1)		N29 E49 D98
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) D34 H71 N169 S250
Catalytic site (residue number reindexed from 1) D34 H71 N169 S250
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1ea7, PDBe:1ea7, PDBj:1ea7
PDBsum1ea7
PubMed14499610
UniProtQ9S3L6

[Back to BioLiP]